Apoptosis Introduction

Apoptosis is the process where damaged cells commit suicide to replace themselves with new cells. If damaged cells are not replaced then diseases, like cancer, can form.

Required Reading

Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics by JF Kerr, AH Wyllie & AR Currie (The original research paper on apoptosis)

Developmental apoptosis in C. elegans by Guillaume Lettre and Michael O. Hengartner (A review on apoptosis in worms)

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells by David L. Vaux, Suzanne Cory & Jerry M. Adams (Connects failing apoptosis to cancer)